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Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study
IntroductionRecent clinical data suggest that early administration of vasopressin analogues may be advantageous compared to a last resort therapy. However, it is still unknown whether vasopressin and… Expand
Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion
IntroductionThe best modality, for continuous renal replacement therapy (CRRT) is currently uncertain and it is poorly understood how transport of different solutes, whether convective or diffusive,… Expand
Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial
IntroductionPrevious findings suggest that a delayed administration of phenylephrine replacing norepinephrine in septic shock patients causes a more pronounced hepatosplanchnic vasoconstriction as… Expand
SHORT-TERM EFFECTS OF PHENYLEPHRINE ON SYSTEMIC AND REGIONAL HEMODYNAMICS IN PATIENTS WITH SEPTIC SHOCK: A CROSSOVER PILOT STUDY
ABSTRACT Clinical studies evaluating the use of phenylephrine in septic shock are lacking. The present study was designed as a prospective, crossover pilot study to compare the effects of… Expand
Improvement of graft function after conversion to once daily tacrolimus of stable kidney transplant patients.
BACKGROUND Chronic renal dysfunction is present in about one quarter of kidney transplant patients at 1 year and in about 90% by 10 years. Nephrotoxicity caused by calcineurin inhibitors is among the… Expand
Presepsin as a potential marker for bacterial infection relapse in critical care patients. A preliminary study
- V. Sargentini, G. Ceccarelli, +10 authors A. Bachetoni
- Clinical chemistry and laboratory medicine
- 15 January 2014
Abstract Background: Systemic bacterial infection carries a high risk of mortality in critical care patients. Improvements in diagnostic procedures are required for effective management of sepsis.… Expand
Once daily tacrolimus formulation: monitoring of plasma levels, graft function, and cardiovascular risk factors.
BACKGROUND Advagraf, an extended release formulation of tacrolimus, is administered once daily during the morning fast. Tacrolimus can be safely converted from the twice daily formulation (Prograf)… Expand
GLIBENCLAMIDE DOSE RESPONSE IN PATIENTS WITH SEPTIC SHOCK: EFFECTS ON NOREPINEPHRINE REQUIREMENTS, CARDIOPULMONARY PERFORMANCE, AND GLOBAL OXYGEN TRANSPORT
Adenosine triphosphate-sensitive potassium channels are important regulators of arterial vascular smooth muscle tone and are implicated in the pathophysiology of catecholamine tachyphylaxis in septic… Expand
Clinical relevance of donor-specific IgG determination by FACS analysis in renal transplantation.
Recovery of chronic renal impairment with sirolimus after lung transplantation.
BACKGROUND Standard immunosuppression after lung transplantation includes calcineurin inhibitors, azathioprine, and steroids. Calcineurin inhibitor administration is associated with an increased… Expand