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Cancer can be considered a genetic disorder of somatic cells. Strong evidence comes from several areas: (1) chromosomal analysis reveals cancer cells have abnormal karyotypes; (2) some inherited(More)
We have proposed that c e l l u l a r senescence is cont ro l led by normal genes that are act ivated or whose funct ions become manifest at the end of the l i f e span of a ce l l . Defects in these(More)
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