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Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery.
  • A. B. Scott
  • Medicine
  • Journal of pediatric ophthalmology and strabismus
  • 1980
TLDR
Injection of botulinum A toxin into extraocular muscle to weaken the muscle appears to be a practical adjunct or alternative to surgical correction of strabismus. Expand
Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients.
We evaluated the ability of low doses of botulinum A toxin, an inhibitor of acetylcholine release at the neuromuscular junction, to denervate and relax the spastic rhabdosphincter in 11 men withExpand
Muscle tension during unrestrained human eye movements.
1. Tensions in the horizontal rectus muscles have simultaneously and continuously been recorded during unrestricted eye movements in four strabismus patients, using force transducers small enough toExpand
Botulinum A toxin injection as a treatment for blepharospasm.
TLDR
Thirty-nine patients with blepharospasm were treated with injections of botulinum A toxin into the lid and brow, finding that tearing, dry-eye symptoms, or transient ptosis occurred in 20% of injections, especially in patients who had had previous eyelid surgery. Expand
Mechanical components of human eye movements.
TLDR
Three lateral rectus muscles of three patients were measured while detached from the globe during strabismus surgery together with the force required to rotate the globe horizontally with both horizontal recti detached to show the pulsatile nature of net active state tension. Expand
Pharmacologic weakening of extraocular muscles.
Botulinum toxin injection of eye muscles to correct strabismus.
  • A. B. Scott
  • Medicine
  • Transactions of the American Ophthalmological…
  • 1981
TLDR
Botulinum A toxin appears to be a safe and useful therapy for strabismus. Expand
Extraocular muscle forces in normal human subjects.
TLDR
This study suggests that a muscle which develops a maximum active force of less than 45 gm would be suspect as paretic, and variations from the normal pattern of reciprocal innervation, reflected in the gradedactive force of individual muscle contraction, may help in understanding some types of oculomotor pathology. Expand
Systemic toxicity of botulinum toxin by intramuscular injection in the monkey
TLDR
Botulinum toxin (Oculinum) was injected intramuscularly into monkeys and the lowest dose that caused systemic toxicity was close to the fatal dose range, 38–42 U/kg. Expand
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