Laminar fluid behavior in microchannels using micropolar fluid theory
- I. Papautsky, J. Brazzle, T. Ameel, A. B. Frazier
- Engineering
- 9 March 1999
Quantification of the Heterogeneity in Breast Cancer Cell Lines Using Whole-Cell Impedance Spectroscopy
- A. Han, Lily Yang, A. B. Frazier
- Biology, MedicineClinical Cancer Research
- 1 January 2007
The findings suggest that microelectrical impedance spectroscopy might find application as a method for quantifying progression of cancer cells without the need for tagging or modifying the sampled cells.
Paramagnetic capture mode magnetophoretic microseparator for high efficiency blood cell separations.
- Ki-Ho Han, A. B. Frazier
- EngineeringLab on a Chip
- 31 January 2006
This paper presents the characterization of continuous single-stage and three-stage cascade paramagnetic capture (PMC) mode magnetophoretic microseparators for high efficiency separation of red and…
Micropatterned surfaces to engineer focal adhesions for analysis of cell adhesion strengthening
- N. Gallant, J. Capadona, A. B. Frazier, D. Collard, Andrés J. García
- Biology, Materials Science
- 8 June 2002
Microcontact printing was used to pattern alkanethiol self-assembled monolayers into arrays of circular adhesive islands within a nonadhesive background, and micropatterning methods to control focal adhesion size and position allowed analysis of the evolution of adhesion strength independently of cell spreading and redistribution of adhesive structures.
Microsystems for isolation and electrophysiological analysis of breast cancer cells from blood.
- Ki-Ho Han, A. Han, A. B. Frazier
- BiologyBiosensors & bioelectronics
- 15 April 2006
Lateral-driven continuous dielectrophoretic microseparators for blood cells suspended in a highly conductive medium.
- Ki-Ho Han, A. B. Frazier
- EngineeringLab on a Chip
- 27 June 2008
The lateral-driven continuous DEP microseparators enable the separation of blood cells based on the lateral DEP force generated by a planar interdigitated electrode array placed at an angle to the direction of flow, overcoming critical drawbacks of DEPmicroseparators.
Electric impedance spectroscopy using microchannels with integrated metal electrodes
- H. E. Ayliffe, A. B. Frazier, R. Rabbitt
- Materials Science
- 1 March 1999
Microelectric impedance measurement systems containing microchannels with integrated gold electrodes were fabricated to enable EI measurements of femtoliter (10/sup -15/) volumes of liquid or gas.…
Effects of rectangular microchannel aspect ratio on laminar friction constant
- I. Papautsky, B. Gale, S. Mohanty, T. Ameel, A. B. Frazier
- EngineeringMOEMS-MEMS
- 19 August 1999
In this paper, the effects of rectangular microchannel aspect ratio on laminar friction constant are described. The behavior of fluids was studied using surface micromachined rectangular metallic…
Whole-Cell Impedance Analysis for Highly and Poorly Metastatic Cancer Cells
- Younghak Cho, Hyun Soo Kim, A. B. Frazier, Z. Chen, D. Shin, A. Han
- BiologyJournal of microelectromechanical systems
- 26 June 2009
It is demonstrated that the metastatic state of HNC cells can be distinguished using the developed muEIS system, which is expected to serve as a powerful tool for future detection and quantification of cancer cells from various tumor stages.
Six-stage cascade paramagnetic mode magnetophoretic separation system for human blood samples
- Youngdo Jung, Yoonsu Choi, Ki-Ho Han, A. B. Frazier
- EngineeringBiomedical microdevices
- 28 March 2010
Experimental results demonstrated that red blood cell separation in the PMMS system at a volumetric flow rate of 28.8 μL / hr, resulting in a separation time of 10.4 min for a 5.0 μL blood sample, was better than expected.
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