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High‐affinity sodium–vitamin C co‐transporters (SVCT) expression in embryonic mouse neurons
The sodium–vitamin C co‐transporters SVCT1 and SVCT2 transport the reduced form of vitamin C, ascorbic acid. High expression of the SVCT2 has been demonstrated in adult neurons and choroid plexusExpand
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Vitamin C uptake and recycling among normal and tumor cells from the central nervous system
Specialized cells transport vitamin C in its reduced form using sodium‐dependent cotransporters (SVCT1 and SVCT2). Additionally, different cells transport the oxidized form of vitamin C,Expand
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Estrogen and progesterone up-regulate glucose transporter expression in ZR-75-1 human breast cancer cells.
Breast cancer incidence increases in women receiving combined estrogen and progesterone therapy. Breast tumors show increased expression of the glucose transporter GLUT1. We determined the effect ofExpand
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The Na+‐dependent l‐ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids
Ascorbic acid (AA) is best known for its role as an essential nutrient in humans and other species. As the brain does not synthesize AA, high levels are achieved in this organ by specific uptakeExpand
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Dehydroascorbic Acid Promotes Cell Death in Neurons Under Oxidative Stress: a Protective Role for Astrocytes
Ascorbic acid (AA), the reduced form of vitamin C, is incorporated into neurons via the sodium ascorbate co-transporter SVCT2. However, this transporter is not expressed in astrocytes, which take upExpand
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Neurotoxin-like compounds from the ichthyotoxic red tide alga Heterosigma akashiwo induce a TTX-like synaptic silencing in mammalian neurons
Abstract Heterosigma akashiwo (Raphidophyceae) is a golden-brown unicellular marine microalgae that has been implicated in massive numbers of fish deaths in natural and cultured populations aroundExpand
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Steroidal composition and cytotoxic activity from fruiting body of Cortinarius xiphidipus
Abstract From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from the crude extract and the cytotoxic effect of ergosta-4, 6, 8(14), 22-tetraen-3-oneExpand
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Transcriptional responses of Mytilus chilensis exposed in vivo to saxitoxin (STX)
Saxitoxin (STX) is one of the main phycotoxins that contribute to paralytic shellfish poisoning (PSP). This toxin is mainly produced by marine microalgae of the genus Alexandrium. There is evidenceExpand
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Study of the ichthyotoxic microalga Heterosigma akashiwo by transcriptional activation of sublethal marker Hsp70b in Transwell co-culture assays
Despite the advance of knowledge about the factors and potential mechanisms triggering the ichthyotoxicity in microalgae, these remain unclear or are controversial for several species (e.g.Expand
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Salinity-Growth Response and Ichthyotoxic Potency of the Chilean Pseudochattonella verruculosa
Despite salmon farmers suffering the worst damage from a harmful algal bloom in Chile’s history (US$800M) due to a massive outbreak of the dictyochophyte Pseudochattonella verruculosa in 2016Expand
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