Obesity : Preventing and managing the global epidemic
- D. S. Akram, A. Astrup, P. Zimmet
- Medicine
- 1 December 2000
Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies
- A. Flint, A. Raben, J. Blundell, A. Astrup
- MedicineInternational Journal of Obesity
- 2000
VAS scores are reliable for appetite research and do not seem to be influenced by prior diet standardization, however, consideration should be given to the specific parameters being measured, their sensitivity and study power.
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
The results show that GLP-1 enhanced satiety and reduced energy intake and thus may play a physiological regulatory role in controlling appetite and energy intake in humans.
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
- X. Pi-Sunyer, A. Astrup, J. Wilding
- MedicineNew England Journal of Medicine
- 1 July 2015
3.0 mg of liraglutide, as an adjunct to diet and exercise, was associated with reduced body weight and improved metabolic control in patients with type 2 diabetes and prediabetes.
A randomized trial of the effects of dietary counseling on gestational weight gain and glucose metabolism in obese pregnant women
- S. Wolff, J. Legarth, K. Vangsgaard, S. Toubro, A. Astrup
- MedicineInternational Journal of Obesity
- 29 January 2008
Restriction of gestational weight gain in obese women is achievable and reduces the deterioration in the glucose metabolism.
Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects.
- A. Raben, T. H. Vasilaras, A. C. Møller, A. Astrup
- Medicine, ChemistryAmerican Journal of Clinical Nutrition
- 1 October 2002
Overweight subjects who consumed fairly large amounts of sucrose (28% of energy), mostly as beverages, had increased energy intake, body weight, fat mass, and blood pressure after 10 wk, and these effects were not observed in a similar group of subjects who consume artificial sweeteners.
Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.
- J. Bruun, A. S. Lihn, B. Richelsen
- Biology, MedicineAmerican Journal of Physiology. Endocrinology and…
- 1 September 2003
The inverse relationship between plasma adip onectin and cytokines in vivo and the cytokine-induced reduction in adiponectin mRNA in vitro suggests that endogenous cytokines may inhibit adiponECTin.
Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials
- R. Christensen, P. K. Kristensen, E. Bartels, H. Bliddal, A. Astrup
- Medicine, PsychologyThe Lancet
- 17 November 2007
Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
- A. Astrup, S. Rössner, M. Lean
- MedicineThe Lancet
- 7 November 2009
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety—effect of obesity and weight reduction
- C. Verdich, S. Toubro, B. Buemann, J. Madsen, J. Holst, A. Astrup
- MedicineInternational Journal of Obesity
- 18 July 2001
Following weight reduction, GLP-1 response in the obese subjects apparently rose to a level between that of obese and lean subjects, and the data suggests that postprandial insulin and GIP responses are key players in short-term appetite regulation.
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