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A subcellular map of the human proteome
Mapping the proteome Proteins function in the context of their environment, so an understanding of cellular processes requires a knowledge of protein localization. Thul et al. used immunofluorescenceExpand
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Toward a Confocal Subcellular Atlas of the Human Proteome*S
Information on protein localization on the subcellular level is important to map and characterize the proteome and to better understand cellular functions of proteins. Here we report on a pilot studyExpand
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Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).
A gene-centric Human Proteome Project has been proposed to characterize the human protein-coding genes in a chromosome-centered manner to understand human biology and disease. Here, we report on theExpand
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A Systematic Characterization of Aquaporin-9 Expression in Human Normal and Pathological Tissues
AQP9 is known to facilitate hepatocyte glycerol uptake. Murine AQP9 protein expression has been verified in liver, skin, epididymis, epidermis and neuronal cells using knockout mice. FurtherExpand
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PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer
Background  The PTCH tumour suppressor gene is involved in the development of nearly all basal cell carcinomas (BCCs) of the skin and a fraction of squamous cell carcinomas (SCCs). A nonconservativeExpand
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Correlation between LRIG1 and LRIG2 expressions and expression of 11 tumor markers, with special reference to tumor suppressors, in CIN and normal cervical epithelium.
OBJECTIVE Novel biological markers LRIG1 and LRIG2 have been associated with favorable as well as poor prognosis, respectively, in different cancer types, including cervical cancer. The aim of thisExpand
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Antibody performance in western blot applications is context-dependent.
An important concern for the use of antibodies in various applications, such as western blot (WB) or immunohistochemistry (IHC), is specificity. This calls for systematic validations usingExpand
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Large-scale protein profiling in human cell lines using antibody-based proteomics.
Human cancer cell lines grown in vitro are frequently used to decipher basic cell biological phenomena and to also specifically study different forms of cancer. Here we present the first large-scaleExpand
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Pituitary-testicular axis in obese men during short-term fasting.
To investigate whether short-term fasting affects the pituitary-testicular axis in obese subjects, 9 massively obese men (Body Mass Index 39.0 +/- 1.3, mean +/- SEM) were given two identical iv GnRHExpand
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Socioeconomic characteristics, housing conditions and criminal offences among women with cervical neoplasia
To investigate the association between cervical neoplasia and socioeconomic factors, housing conditions and criminal offences.
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