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  • Influence
Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies.
BACKGROUND Saturated fatty acid (SFA) intake increases plasma LDL-cholesterol concentrations; therefore, intake should be reduced to prevent coronary heart disease (CHD). Lower habitual intakes ofExpand
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Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire.
  • F. Hu, E. Rimm, +5 authors W. Willett
  • Biology, Medicine
  • The American journal of clinical nutrition
  • 1 February 1999
BACKGROUND Recently, the analysis of dietary patterns has emerged as a possible approach to examining diet-disease relations. OBJECTIVE We examined the reproducibility and validity of dietaryExpand
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Trans-fatty acids intake and risk of myocardial infarction.
BACKGROUND Concern that trans-fatty acids formed in the partial hydrogenation of vegetable oils may increase the risk of coronary disease has existed for several decades, but direct evidence on thisExpand
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Diet, alcohol, and smoking and the occurrence of hyperplastic polyps of the colon and rectum (United States)
Hyperplastic polyps of the colon reveal a geographic distribution similar to that of colorectal cancer and adenomatous polyps. However, unlike adenomas—known precursors of colorectal cancer—little isExpand
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Primary infection with the Epstein‐Barr virus and risk of multiple sclerosis
To determine whether multiple sclerosis (MS) risk increases following primary infection with the Epstein‐Barr virus (EBV), we conducted a nested case‐control study including 305 individuals whoExpand
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Smoking is a risk factor for early conversion to clinically definite multiple sclerosis
Background Cigarette smoking increases the risk for development of multiple sclerosis and modifies the clinical course of the disease. In this study, we determined whether smoking is a risk factorExpand
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Integrating risk factors
Background: Individuals with high levels of antibodies to the Epstein–Barr virus nuclear antigen 1 (EBNA-1) have an increased risk of developing multiple sclerosis (MS), but this association could beExpand
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Plasma urate and risk of Parkinson's disease.
Oxidative stress contributes to dopaminergic neuron degeneration in Parkinson's disease. Urate, a potent antioxidant, could be neuroprotective. To determine whether higher plasma concentrations ofExpand
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Peripheral inflammatory biomarkers and risk of Parkinson's disease.
Experimental and postmortem evidence indicates a role of neuroinflammation in the pathogenesis of Parkinson's disease. The authors prospectively examined whether plasma concentrations of inflammatoryExpand
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Relation of Consumption of Vitamin E, Vitamin C, and Carotenoids to Risk for Stroke among Men in the United States
Considerable evidence supports the hypothesis that vitamin E reduces the risk for atherosclerosis (1). Vitamin E inhibits the proliferation of smooth-muscle cells in vitro (2) and increases theExpand
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