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Snake venom components and their applications in biomedicine
Abstract.Snake envenomation is a socio-medical problem of considerable magnitude. About 2.5 million people are bitten by snakes annually, more than 100,000 fatally. However, although bites can beExpand
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Highly permeable and selective pore-spanning biomimetic membrane embedded with aquaporin Z.
A highly permeable yet highly selective pore-spanning biomimetic membrane embedded with aquaporin Z is molecularly designed and constructed via a combination of pressure-assisted vesicle adsorptionExpand
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An aquaporin-based vesicle-embedded polymeric membrane for low energy water filtration
Aquaporins (AQPs) are transmembrane water channel proteins that serve as nano-filters to selectively transport water molecules through plasma membranes in living cells at high speeds while blockingExpand
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Toxins in anti-nociception and anti-inflammation.
The use of toxins as novel molecular probes to study the structure-function relationship of ion-channels and receptors as well as potential therapeutics in the treatment of wide variety of diseasesExpand
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Postsynaptic short-chain neurotoxins from Pseudonaja textilis. cDNA cloning, expression and protein characterization.
Two lethal proteins, which specifically bind to the nAChR from Torpedo californica, were isolated from the venom of Pseudonaja textilis, the common brown snake from Australia. The isolated proteinsExpand
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Structure and phylogeny of the venom group I phospholipase A(2) gene.
Phospholipases A(2) (PLA(2)s) catalyzing the hydrolysis of phospholipids form a family of proteins with diverse physiological and pharmacological properties. While there have been several reports onExpand
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Stabilization and immobilization of aquaporin reconstituted lipid vesicles for water purification.
Aquaporins are water channel proteins in biological membranes that have extraordinary water permeability and selectivity. In this work, we have demonstrated that one of their family members,Expand
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A layer-by-layer self-assembly approach to developing an aquaporin-embedded mixed matrix membrane
Aquaporin (AQP) is a water channel protein in biological membranes that possesses exceptional water selectivity and permeability. The AQP-embedded biomimetic membrane can be potentially used in waterExpand
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Recombinant antitoxic and antiinflammatory factor from the nonvenomous snake Python reticulatus: phospholipase A2 inhibition and venom neutralizing potential.
From the serum of the nonvenomous snake Python reticulatus, a new phospholipase A(2) (PLA(2)) inhibitor termed phospholipase inhibitor from python (PIP) was purified by sequential chromatography andExpand
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Snake postsynaptic neurotoxins: gene structure, phylogeny and applications in research and therapy.
Snake venoms are complex mixtures of biologically active polypeptides that target a variety of vital physiological functions in mammals. alpha-Neurotoxins, toxins that cause paralysis by binding toExpand
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