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Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPPExpand
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The Human Proteome Project: Current State and Future Direction
The Human Proteome Organization urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators. Expand
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Protein‐protein interactions as a target for drugs in proteomics
Protein‐protein interactions play a central role in numerous processes in the cell and are one of the main fields of functional proteomics. This review highlights the methods of bioinformatics andExpand
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Identification of glycosaminoglycan‐binding sites within hepatitis C virus envelope glycoprotein E2 *
Summary.  Heparan sulphate is one of the candidate receptors for hepatitis C virus (HCV). Envelope glycoproteins of HCV have been proposed to be responsible for recognition and binding with cellExpand
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[CARD15 and TLR4 genes polymorphisms in atopic bronchial asthma].
In order to investigate whether single nucleotide polymorphisms G(+2722)C and 3020insC in CARD15 gene and Asp299Gly in TLR4 gene contribute to atopic bronchial asthma we performed a comparativeExpand
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Biospecific irreversible fishing coupled with atomic force microscopy for detection of extremely low‐abundant proteins
In the absence of an analog of PCR for proteins, the concentration detection limit (DL) becomes a real challenge. The problem may be solved by means of a combination of biospecific irreversibleExpand
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AFM fishing nanotechnology is the way to reverse the Avogadro number in proteomics
Future development of proteomics may be hindered by limitations in the concentration sensitivity of widespread technological approaches. The concentration sensitivity limit (CSL) of currently usedExpand
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PPLine: An Automated Pipeline for SNP, SAP, and Splice Variant Detection in the Context of Proteogenomics.
The fundamental mission of the Chromosome-Centric Human Proteome Project (C-HPP) is the research of human proteome diversity, including rare variants. Liver tissues, HepG2 cells, and plasma wereExpand
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Exome-driven characterization of the cancer cell lines at the proteome level: the NCI-60 case study.
Cancer genome deviates significantly from the reference human genome, and thus a search against standard genome databases in cancer cell proteomics fails to identify cancer-specific protein variants.Expand
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Nanobiotechnologies in medicine: Nanodiagnostics and nanodrugs
  • A. Archakov
  • Chemistry, Medicine
  • Biomeditsinskaia khimiia
  • 24 March 2010
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