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Antioxidant Intake and Antitumor Therapy: Toward Nutritional Recommendations for Optimal Results
TLDR
The evidence at the moment suggests that the supplementation or restriction of exogenous antioxidants during cancer treatment, as appropriate, could contribute to improving its efficiency and the convenience of administration of antioxidants still remains a very controversial issue.
MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy
TLDR
The hypothesis that MGMT promoter methylation status but not MGMT expression may be a predictive biomarker in the treatment of patients with glioblastoma is supported.
Relationship of body mass index and body fat distribution with postural balance and risk of falls in Spanish postmenopausal women
TLDR
Postural instability is associated with obesity and uniform and android body fat distribution types (waist-to-hip ratio > 0.76) in Spanish postmenopausal women aged 50 to 65 years and it is suggested that a BMI of 25 kg/m2 or higher and androidBody fat distribution can be considered as independent risk factors for falls.
5-Fluorouracil derivatives: a patent review
TLDR
The search for less toxic 5-FU derivatives, which diminish or circumvent some of its disadvantages, has allowed the development of selective antitumor prodrugs and novel methods for tissue-specific drug delivery.
Novel Drug Delivery System Based on Docetaxel-Loaded Nanocapsules as a Therapeutic Strategy Against Breast Cancer Cells
TLDR
Docetaxel-loaded lipid nanocapsules significantly enhanced the decrease in IC50 rate, and the treated cells evidenced apoptosis and a premature progression of the cell cycle from G(1) to G(2)-M phase.
Analysis of the distribution of human CD38 and of its ligand CD31 in normal tissues.
TLDR
The above results were enriched by the analysis of the expression of the two molecules on purified populations including mononuclear cells from the lamina propria of the gastro-intestinal tract and broncho-alveolar lavage lymphocytes.
Doxorubicin-loaded nanoparticles: new advances in breast cancer therapy.
TLDR
An overview of doxorubicin nanoplatform-based delivery systems and the principal advances obtained in breast cancer chemotherapy is provided.
Growth inhibition, G1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives
TLDR
Support is provided for the use of these novel compounds as new weapons in the fight against breast cancer by demonstrating induction of apoptosis by the annexin-V-based assay and confirmed using DNA fragmentation analysis on MCF-7 cells.
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