Anatomical Correlates of Functional Plasticity in Mouse Visual Cortex
The experiments of this paper were directed toward understanding whether anatomical changes accompany functional plasticity in the developing visual cortex of the mouse, as they do in higher mammals.
Rapid remodeling of axonal arbors in the visual cortex.
Reconstruction of single geniculocortical axonal arbors in the cat after either brief or prolonged monocular occlusion revealed striking axonal rearrangements in both instances, suggesting that axonal branches bearing synapses respond quickly to changing patterns of neuronal activity.
Requirement for subplate neurons in the formation of thalamocortical connections
It is shown that early in development the deletion of subplate neurons located beneath visual cortex prevents axons from the lateral geniculate nucleus of the thalamus from recognizing and innervating visual cortex, their normal target.
Development of individual geniculocortical arbors in cat striate cortex and effects of binocular impulse blockade
Results reveal that sparse but widely extending branches characteristic of young arbors are eliminated during normal development at the same time as selected portions of the arbor grow considerably in length and complexity.
Ultrastructural Evidence for Synaptic Interactions between Thalamocortical Axons and Subplate Neurons
Observations provide direct evidence that thalamocortical axons make synaptic contacts with subplate neurons, the only cell type within the subplate possessing mature dendrites and dendritic spines; they suggest that functional interactions between thalamic axons and sub plate neurons could play a role in the establishment of appropriate thalamOCortical connections.
Emergence of ocular dominance columns in cat visual cortex by 2 weeks of age
- M. Crair, J. Horton, A. Antonini, M. Stryker
- BiologyThe Journal of comparative neurology
- 5 February 2001
The functional and anatomic data suggest that ocular dominance column formation begins between P7 and P14, approximately a week earlier than previously believed, and reveal an early developmental bias toward contralateral eye afferents.
Plasticity of geniculocortical afferents following brief or prolonged monocular occlusion in the cat
Compared the geniculocortical connectivity in normal kittens with that following brief or prolonged periods of occlusion of vision in one eye, these findings provide further evidence for rapid, activity‐dependent remodeling of afferents during development.
Pioneer neurons and target selection in cerebral cortical development.
Relation Between Putative Transmitter Phenotypes and Connectivity of Subplate Neurons During Cerebral Cortical Development
Observations indicate that subplate neurons immunoreactive for NPY, SRIF and CaBP are likely to be interneurons exclusively, and that at least some projection sub plate neurons might use an excitatory amino acid as a neurotransmitter.
Morphology of Single Geniculocortical Afferents and Functional Recovery of the Visual Cortex after Reverse Monocular Deprivation in the Kitten
- A. Antonini, D. C. Gillespie, M. Crair, M. Stryker
- Biology, PsychologyJournal of Neuroscience
- 1 December 1998
These analyses demonstrate that closure of the OND eye caused a substantial shrinkage of the arbors serving that eye, and it was found that reopening the OD eye induced regrowth only in some arbors, whereas others appeared to be largely unaffected and continued to have the characteristics of deprived arbors.