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Phytotoxins Produced by Fungi Associated with Grapevine Trunk Diseases
- A. Andolfi, L. Mugnai, J. Luque, G. Surico, A. Cimmino, A. Evidente
- Environmental ScienceToxins
- 1 December 2011
An overview of the toxins produced by the most serious of these vine wood pathogens: Eutypa lata, Phaeomoniella chlamydospora,Phaeoacremonium aleophilum and some taxa in the Botryosphaeriaceae family are presented and how these toxins produce decline symptoms are examined.
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of…
- D. Lamoral-Theys, A. Andolfi, A. Evidente
- Biology, ChemistryJournal of medicinal chemistry
- 22 October 2009
The results of the current study make lycorine an excellent lead for the generation of compounds able to combat cancers, which are naturally resistant to proapoptotic stimuli, such as glioblastoma, melanoma, non-small-cell-lung cancers, and metastatic cancers, among others.
Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
- Gwendoline Van Goietsenoven, A. Andolfi, A. Evidente
- Biology, ChemistryJournal of natural products
- 15 June 2010
The data from the present study revealed that lycorine, amarbellisine, haemanthamine, and Haemanthidine are potentially useful chemical scaffolds to generate further compounds to combat cancers associated with poor prognoses, especially those naturally resistant to apoptosis, such as glioblastoma, melanoma, non-small-cell lung, and metastatic cancers.
Stagonolides B-F, nonenolides produced by Stagonospora cirsii, a potential mycoherbicide of Cirsium arvense.
- A. Evidente, A. Cimmino, A. Berestetskiy, G. Mitina, A. Andolfi, A. Motta
- ChemistryJournal of natural products
Five new nonenolides, named stagonolides B-F (2-6), were isolated and characterized using spectroscopic methods, and showed no toxicity to C. arvense and Sonchus arvensis, whereas stagonspora cirsii (1) was highly toxic.
Interaction between Pseudomonas savastanoi pv. savastanoi and Pantoea agglomerans in olive knots
Results of a survey of olive knot disease in central Italy in 2002 and 2003 showed that Pantoea agglomerans was found associated with the pathogen Pseudomonas savastanoi pv. savastanoi (Ps.…
Brefeldin A and α,β-dehydrocurvularin, two phytotoxins from Alternaria zinniae, a biocontrol agent of Xanthium occidentale
Absolute configurations of fungal and plant metabolites by chiroptical methods. ORD, ECD, and VCD studies on phyllostin, scytolide, and oxysporone.
This study shows that in the case of flexible and complex natural products only a concerted application of more than a single chiroptical technique permits unambiguous assignment of absolute configuration.
(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt.
Lipophilic phytotoxins produced by Neofusicoccum parvum, a grapevine canker agent.
Four phytotoxins produced by Neofusicoccum parvum were isolated and identified by spectroscopic methods as (3 R ,4 R )-(-)-4-hydroxymellein, isosclerone and tyrosol, and all four metabolites showed Phytotoxic activity on tomato plants.
Production of phytotoxic metabolites by five species of Botryosphaeriaceae causing decline on grapevines, with special interest in the species Neofusicoccum luteum and N. parvum
- S. Martos, A. Andolfi, J. Luque, L. Mugnai, G. Surico, A. Evidente
- Environmental Science, BiologyEuropean Journal of Plant Pathology
- 22 January 2008
Results suggest that phytotoxic metabolites could be involved in the virulence of both species in planta.