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Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflammed liver
Increased expression of MPO in damaged rat and human liver is due to recruited elastase positive NGs, as demonstrated in normal rat liver and acutely injured human liver.
Interferon-λ4 (IFNL4) Transcript Expression in Human Liver Tissue Samples
Data indicate that HCV infection in particular might activate IFNL4 transcription in the liver, and provides a possible explanation as to why hepatitis C patients show ISG stimulation in their livers in the apparent absence of an induction of other IFN subtypes.
A Case Report of a Patient with Hereditary Hemorrhagic Telangiectasia Treated Successively with Thalidomide and Bevacizumab
A dramatic improvement of a patient with a high transfusion frequency due to severe recurrent anemia successively treated with thalidomide and bevacizumab is described.
Induction of chemokines and cytokines before neutrophils and macrophage recruitment in different regions of rat liver after TAA administration
In conclusion, single-dose TAA administration induces a sequence of events with a defined upregulation of gene expression of inflammatory chemokines and cytokines and a transient accumulation of NGs within the portal area and macrophages along the sinusoids throughout the liver.
Vitamin D status and serum ferritin concentration in chronic hepatitis C virus type 1 infection
The circulating 25‐hydroxylated form of vitamin D3, 25(OH)D, and serum ferritin concentrations have been described to be associated with disease progression in chronic hepatitis C. Both parameters
Ferritin L is the Sole Serum Ferritin Constituent and a Positive Hepatic Acute-Phase Protein
It is demonstrated that FTL is the only rat serum ferritin whose release into circulation from the hepatocytes is increased by the effect of AP cytokines (e.g., IL-6), and FTH expression is intracellular in both under physiological and AP conditions.
Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines.
AIM To study KRAS/BRAF mutations in colorectal-cancer (CRC) that influences the efficacy of treatment. To develop strategies for overcoming combination of treatment. METHODS Five colonic cell-lines
High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia
It is suggested that HBT should be considered in the clinical management of patients with suspected functional dyspepsia and in cases of positive HBTs, a potential causal therapy can be initiated.
Serum vitamin D but not zinc levels are associated with different disease activity status in patients with inflammatory bowel disease
Serum 25(OH)D levels, but not serum zinc levels, may be an additional useful and noninvasive marker for characterizing different disease activity status of IBD patients.
Identification of CD68(+) neutrophil granulocytes in in vitro model of acute inflammation and inflammatory bowel disease.
Investigation of expression of CD-68 in human peripheral blood mononuclear cells, neutrophil granulocytes and in inflamed intestinal tissue samples for comparison identifies CD- 68(+) NGs in peripheral blood and inflamed colonic mucosa.