• Publications
  • Influence
Guidelines for the use and interpretation of assays for monitoring autophagy
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
  • 5,282
  • 446
  • PDF
Autophagosomes form at ER–mitochondria contact sites
Autophagy is a tightly regulated intracellular bulk degradation/recycling system that has fundamental roles in cellular homeostasis. Autophagy is initiated by isolation membranes, which form andExpand
  • 1,023
  • 70
  • PDF
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
  • 2,246
  • 38
  • PDF
Autophagy Defends Cells Against Invading Group A Streptococcus
We found that the autophagic machinery could effectively eliminate pathogenic group A Streptococcus (GAS) within nonphagocytic cells. After escaping from endosomes into the cytoplasm, GAS becameExpand
  • 978
  • 36
Functional Differences among FimA Variants of Porphyromonas gingivalis and Their Effects on Adhesion to and Invasion of Human Epithelial Cells
ABSTRACT Fimbriae of Porphyromonas gingivalis, a periodontopathogen, play an important role in its adhesion to and invasion of host cells. The fimA genes encoding fimbrillin (FimA), a subunit proteinExpand
  • 139
  • 13
  • PDF
Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease
BackgroundNon-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome that is closely associated with multiple factors such as obesity, hyperlipidemia and type 2Expand
  • 124
  • 13
BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
The BRCA1 tumor suppressor associates with both the DROSHA microRNA maturation complex and primary miRNA transcripts, and promotes transcript processing.
  • 152
  • 10
  • PDF
Variations of Porphyromonas gingivalis fimbriae in relation to microbial pathogenesis.
OBJECTIVES Periodontal disease is an infectious disorder caused by a small subset of periodontal pathogens including Porphyromonas gingivalis. Accumulated evidences show that the expression of P.Expand
  • 189
  • 9
Bacterial adhesins to host components in periodontitis.
  • A. Amano
  • Medicine
  • Periodontology
  • 1 February 2010
  • 89
  • 8
Serotype distribution of Streptococcus mutans a pathogen of dental caries in cardiovascular specimens from Japanese patients.
The involvement of oral bacteria in the pathogenesis of cardiovascular disease has been studied, with Streptococcus mutans, a pathogen of dental caries, detected in cardiovascular lesions at a highExpand
  • 59
  • 7
  • PDF