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How Does the Quality of Phospholipidosis Data Influence the Predictivity of Structural Alerts?
The ability of drugs to induce phospholipidosis (PLD) is linked directly to their molecular substructures: hydrophobic, cyclic moieties with hydrophilic, peripheral amine groups. Expand
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Delivering natural products and biotherapeutics to improve drug efficacy.
Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including theExpand
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Where traditional drug discovery meets modern technology in the quest for new drugs
Identifying novel compounds or improving bioavailability of drugs requires extensive screening, in vitro and in vivo testing and subsequent commercialisation. Traditional methods can be labourExpand
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