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Non-invasive evaluation of liver fibrosis using transient elastography.
TLDR
TE appears to be an excellent tool for early detection of cirrhosis and may have prognostic value in this setting and could be useful for monitoring fibrosis progression and regression in the individual case, but more data are awaited for this application. Expand
Short statement of the first European Consensus Conference on the treatment of chronic hepatitis B and C in HIV co-infected patients.
TLDR
A European Consensus Conference to review current knowledge on the treatment of chronic hepatitis B and C in HIV co-infected patients with the view to developing this consensus statement. Expand
A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel
TLDR
A comprehensive review of the literature was used to gather country‐specific data on risk factors, prevalence, number of diagnosed individuals and genotype distribution of the hepatitis C virus (HCV) infection in selected European countries, Canada and Israel. Expand
Natural history of compensated viral cirrhosis: a prospective study on the incidence and hierarchy of major complications
TLDR
These results indicate significant morbidity and mortality during the first decade after diagnosis of compensated cirrhosis due to HBV and/or HCV, and identify hepatocellular carcinoma as the most frequent and life threatening complication, particularly in HCV positive cases. Expand
The global health burden of hepatitis C virus infection
TLDR
A framework to evaluate the HCV-infected populations in countries around the world and to understand the cause and effect relation-ship between the key assumptions and future trends is created, which may help to target new public health strategies. Expand
Natural history and prognostic factors for chronic hepatitis type B.
TLDR
Findings indicate that patients with severe chronic active hepatitis and persistent hepatitis B virus replication are at very high risk of rapid progression to cirrhosis. Expand
Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis.
TLDR
MTP may play a central role in HCV-related steatosis, being modulated by different genotype-specific mechanisms, mainly hyperinsulinemia in non-HCV-3 patients, and more profound and direct virus-related effects in HCv-3-infected individuals. Expand
Non invasive fibrosis biomarkers reduce but not substitute the need for liver biopsy.
TLDR
A set of algorithms that combine sequentially indirect non-invasive markers of liver fibrosis, reaching 90%-95% diagnostic accuracy with significant reduction in the need for liver biopsy are proposed. Expand
Long‐term follow‐up of the hepatitis C HENCORE cohort: response to therapy and occurrence of liver‐related complications
TLDR
Long‐term follow up of HCV patients indicates that virological response persists over time and is associated with a very low incidence of liver complications. Expand
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