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A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually. To identify genetic factors that modify disease risk, we conducted a genome-wide associationExpand
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Dietary polyphenol intake in Europe: the European Prospective Investigation into Cancer and Nutrition (EPIC) study
AbstractBackground/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protectiveExpand
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Lung cancer and cigarette smoking in Europe: An update of risk estimates and an assessment of inter‐country heterogeneity
Ten case‐control studies have been carried out in 6 European countries to investigate the major risk factors for lung cancer. Carcinogenic effect from cigarette smoke was the most relevant interestExpand
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Adherence to the Mediterranean diet reduces mortality in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain).
Epidemiological studies show that adherence to a Mediterranean diet (MD) increases longevity; however, few studies are restricted to Mediterranean populations or explore the effect of a MD patternExpand
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Polychlorinated biphenyls in Spanish adults: determinants of serum concentrations.
BACKGROUND Polychlorinated biphenyls (PCBs) are persistent compounds that may pose an environmental hazard to humans, food being the main source of exposure for the general population. OBJECTIVE ToExpand
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Consistent but indirect evidence has implicated genetic factors in smoking behavior. We report meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium (n =Expand
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Adherence to a Mediterranean diet is associated with reduced 3-year incidence of obesity.
Few studies have prospectively examined dietary patterns and adult weight change, and results to date are inconsistent. This study examines whether a Mediterranean diet (MD) pattern is associatedExpand
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Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study.
BACKGROUND The Mediterranean dietary pattern is believed to protect against cancer, although evidence from cohort studies that have examined particular cancer sites is limited. OBJECTIVE We aimedExpand
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Multicentric study on malignant pleural mesothelioma and non-occupational exposure to asbestos
Insufficient evidence exists on the risk of pleural mesothelioma from non-occupational exposure to asbestos. A population-based case–control study was carried out in six areas from Italy, Spain andExpand
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Multiple ADH genes are associated with upper aerodigestive cancers
Alcohol is an important risk factor for upper aerodigestive cancers and is principally metabolized by alcohol dehydrogenase (ADH) enzymes. We have investigated six ADH genetic variants in over 3,800Expand
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