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Anticancer activity of Moringa oleifera mediated silver nanoparticles on human cervical carcinoma cells by apoptosis induction.
Comparative inhibitory potential of selected dietary bioactive polyphenols, phytosterols on CYP3A4 and CYP2D6 with fluorometric high-throughput screening
- T. Vijayakumar, Ramasamy Mohan Kumar, A. Agrawal, G. Dubey, K. Ilango
- Biology, ChemistryJournal of Food Science and Technology
- 1 July 2015
In comparison of in vitro inhibitory potential on CYP3A4 and CYP2D6, consumption of food or herbal or dietary supplements containing quercetin and gallic acid without any limitation should be carefully considered when narrow therapeutic drugs are administered together.
Amelioration of Age Associated Neuroinflammation on Long Term Bacosides Treatment
- Manisha Rastogi, R. Ojha, B. P. Devi, Aabha Aggarwal, A. Agrawal, G. Dubey
- Biology, MedicineNeurochemical Research
- 1 April 2012
The results of the present study suggest that bacosides possess immense potential to act as a neuroprotective agent due to its pleiotropic action for the prevention of ageing complications and SDAT progression.
Prevention of age-associated neurodegeneration and promotion of healthy brain ageing in female Wistar rats by long term use of bacosides
- Manisha Rastogi, R. Ojha, P. Prabu, B. P. Devi, A. Agrawal, G. Dubey
- Biology, MedicineBiogerontology
- 1 April 2012
The results of the present study suggest that bacosides may act as a potential therapeutic intervention in forestalling the deleterious effects of ageing and preventing the age associated pathologies like SDAT.
Neuroprotective Effect of Curcuminoids Against Inflammation-Mediated Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease
- R. Ojha, Manisha Rastogi, B. P. Devi, A. Agrawal, G. Dubey
- BiologyJournal of Neuroimmune Pharmacology
- 21 April 2012
The findings suggest that curcuminoids exert a neuroprotective effect against MPTP-induced dopaminergic neurodegeneration through its anti-inflammatory action and thus holds immense potential as a therapeutic candidate for the prevention and management of PD.
Management of Cognitive Determinants in Senile Dementia of Alzheimer’s Type: Therapeutic Potential of a Novel Polyherbal Drug Product
Administration of the test formulation for a period of 12 months was effective in improving cognitive functions in the SDAT patients, when compared to the donepezil-treated group, as determined by the DSS.
Comparative evaluation of fosinopril and herbal drug Dioscorea bulbifera in patients of diabetic nephropathy.
- R. Singh, M. Rajak, B. Ghosh, A. Agrawal, G. Dubey
- MedicineSaudi journal of kidney diseases and…
- 1 July 2013
Dioscorea bulbifera was more effective than fosinopril in controlling blood pressure, glycemia, cholesterolemia and inflammatory state in diabetic nephropathy and both agents decreased proteinuria.
Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain
- Manisha Rastogi, R. Ojha, G. Rajamanickam, A. Agrawal, A. Aggarwal, G. Dubey
- Biology, ChemistryFree radical research
- 1 January 2008
Results suggest that curcuminoids exhibit a protective effect by accelerating antioxidant defense mechanisms and attenuating mitochondrial dysfunction in the brain of diabetic rats, and may be used as a promising therapeutic agent in preventing and/or delaying the progression of diabetic complications in the head.
Metaflammatory responses during obesity: Pathomechanism and treatment.