Role of oxidative stress in female reproduction
The role OS plays in normal cycling ovaries, follicular development and cyclical endometrial changes is reviewed and female infertility and how it influences the outcomes of assisted reproductive techniques is discussed.
Role of reactive oxygen species in the pathophysiology of human reproduction.
The effects of oxidative stress on female reproduction: a review
- A. Agarwal, Anamar Aponte-Mellado, B. Premkumar, A. Shaman, Sajal Gupta
- BiologyReproductive Biology and Endocrinology
- 29 June 2012
The impact of OS on assisted reproductive techniques (ART) will be addressed, in addition to the possible benefits of antioxidant supplementation of ART culture media to increase the likelihood for ART success.
Effect of Oxidative Stress on Male Reproduction
- A. Agarwal, Gurpriya Virk, C. Ong, S. D. du Plessis
- BiologyThe World Journal of Men's Health
- 1 April 2014
This review highlights the mechanisms of ROS production, the physiological and pathophysiological roles of ROS in relation to the male reproductive system, and recent advances in diagnostic methods; it also explores the benefits of using antioxidants in a clinical setting.
A unique view on male infertility around the globe
- A. Agarwal, Aditi A. Mulgund, A. Hamada, M. Chyatte
- MedicineReproductive Biology and Endocrinology
- 26 April 2015
At least 30 million men worldwide are infertile with the highest rates in Africa and Eastern Europe, and a novel and unique way to calculate the distribution of male infertility around the world is demonstrated.
Role of reactive oxygen species in male infertility.
Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility.
Role of sperm chromatin abnormalities and DNA damage in male infertility.
Screening for sperm DNA damage may provide useful information in cases of male idiopathic infertility and in those men pursuing assisted reproduction, and treatment should include methods for prevention of spermDNA damage.
REVIEW ARTICLE: Clinical Relevance of Oxidative Stress in Male Factor Infertility: An Update
- A. Agarwal, K. Makker, R. Sharma
- Biology, MedicineAmerican Journal of Reproductive Immunology
- 12 December 2007
The need of ROS in normal sperm physiology, the mechanism of production of ROS and its pathophysiology in relation to male reproductive system are discussed and the benefits of incorporating antioxidants in clinical and experimental settings have been enumerated.
Mechanism, measurement, and prevention of oxidative stress in male reproductive physiology.
The detrimental effects of OS on male fertility, measurement of OS and effective ways to decrease or eliminate them completely are analyzed and other systems of the body are provided, which may be applied to future research in the field of reproductive biology.