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DNA methylation epigenotypes in breast cancer molecular subtypes
TLDR
Evidence is provided that well-defined DNA methylation profiles enable breast cancer subtype prediction and support the utilization of this biomarker for prognostication and therapeutic stratification of patients with breast cancer.
Role of cytochrome P-450 genetic polymorphisms in oral carcinogenesis.
TLDR
This review analyzes and updates the available evidence in the literature regarding the polymorphisms of CYP genes in relation to the susceptibility of developing oral cancer and suggests that smoking is a major risk factor.
Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections
TLDR
The results show the effectiveness of DL for predicting nBAP1 expression in UM on the basis of H&E sections only, and demonstrates a high capacity of artificial intelligence-related techniques for automated prediction on the based of histomorphology, and may be translatable into routine histology laboratories.
Immunogenomic profile of colorectal cancer response to immune checkpoint blockade
TLDR
It is proposed that anti-PD1 agents release the PD1-PDL1 interaction between CD8 T cells and macrophages thus promoting cytotoxic anti-tumour activity.
Cytometric analysis of oral scrapings of patients with oral lichen planus
TLDR
A. Acha‐Sagredo, Y. Jiménez, J. Echebarria‐Goicouria and J. M. Aguirre‐Utric analysis of oral scrapings of patients with oral lichen planus shows clear signs of phytochemical similarity to that in animals treated with this substance.
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