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Pepsin assay: A marker for reflux in pediatric glue ear
Objective To evaluate if analysis of pepsin/pepsinogen in middle ear effusions can be considered a diagnostic marker for laryngopharyngeal reflux (LPR) in children with otitis media with effusionExpand
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Clinical evaluation of pepsin for laryngopharyngeal reflux in children with otitis media with effusion.
OBJECTIVE We sought to evaluate the clinical role of pepsin for laryngopharyngeal reflux (LPR) in children with otitis media with effusion (OME). METHODS Pepsin/pepsinogen and fibrinogen wereExpand
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Apparent diffusion coefficient of the vertebral bone marrow in children with Gaucher's disease type I and III
PurposeTo assess apparent diffusion coefficient (ADC) as a quantitative parameter for detection of vertebral bone marrow infiltration in children with Gaucher’s disease type I and III.Material andExpand
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Regression of fibrosis in paediatric autoimmune hepatitis: morphometric assessment of fibrosis versus semiquantiatative methods
BackgroundRegression of hepatic fibrosis in patients with autoimmune hepatitis (AIH) has been described in response to immunosuppressive therapy. These studies, however, besides being few in number,Expand
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Proton MR Spectroscopy of the brain in children with neuronopathic Gaucher’s disease
ObjectiveTo assess the clinical usefulness of proton magnetic resonance spectroscopy (1H-MRS) in children with neuronopathic Gaucher’s disease (NGD).MethodsA prospective study was conducted upon 21Expand
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Assessment of the liver and spleen in children with Gaucher disease type I with diffusion-weighted MR imaging.
PURPOSE To assess hepatic and splenic apparent diffusion coefficient (ADC) in children with Gaucher disease type I with diffusion-weighted MR imaging and to correlate hepatic and splenic ADC withExpand
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Morphometric assessment of liver fibrosis may enhance early diagnosis of biliary atresia
BackgroundNeonatal cholestasis syndrome is considered as a major challenge in pediatric practice. This study was undertaken to investigate the value of morphometric assessment of hepatic fibrosis inExpand
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Immunohistochemical identification of HCV target antigen in paraffin‐embedded liver tissue: reproducibility and staining patterns
Abstract: Background: Immunohistochemical staining has been applied successfully to detect hepatitis C virus (HCV) antigen in fresh frozen tissue. In paraffin‐embedded tissues, however, minimalExpand
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Plasma Endothelin-1 Concentrations in Children With Cirrhosis and Their Relationship to Renal Function and the Severity of Portal Hypertension
Background Plasma endothelin-1 (ET-1) is a potent vasoconstrictor peptide involved in the pathogenesis of several disorders. Endothelin-1 concentrations are increased in adult patients withExpand
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Multi-parametric MR imaging using apparent diffusion coefficient and fat fraction in quantification of bone marrow in pediatrics with Gaucher disease.
PURPOSE To assess multi-parametric MR imaging with apparent diffusion coefficient (ADC) and fat fraction (FF) in detection and quantification of bone marrow involvement in pediatric patients withExpand
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