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Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer
Among patients with stage III epithelial ovarian cancer, the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery resulted in longer recurrence‐free survival and overall survival than surgery alone and did not result in higher rates of side effects.
Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers
The data indicate that neoadjuvant immunotherapy may have the potential to become the standard of care for a defined group of colon cancer patients when validated in larger studies with at least 3 years of disease-free survival data.
Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial
Adjuvant HIPEC is assumed to reduce the expected 25 % absolute risk of PC in patients with T4 or perforated colon cancer to a risk of 10 %.
Cytoreduction and HIPEC in The Netherlands: Nationwide Long-term Outcome Following the Dutch Protocol
The results underline the safety and efficacy of cytoreduction and HIPEC for PC from colorectal cancer and pseudomyxoma peritonei treated according to the Dutch HIPEC protocol.
Hand‐assisted laparoscopic versus open approach in colorectal surgery: a systematic review
- A. Aalbers, A. Doeksen, M. I. van Berge Henegouwen, W. Bemelman
- Medicine, ChemistryColorectal disease : the official journal of the…
- 1 April 2010
Aim This systematic review was performed to answer the question whether hand‐assisted laparoscopic surgery (HALS) can preserve the advantages of laparoscopic compared with open surgery in colorectal…
Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
In patients with PC from lymph node positive colorectal carcinoma, perioperative systemic chemotherapy is associated with increased OS and PFS, although this difference may be partly explained by the occurrence of major postoperative complication; with no evidence of difference in P FS, OS and systemic recurrence rate by timing of systemic chemotherapy.
Factors affecting outcomes following pelvic exenteration for locally recurrent rectal cancer
This study analysed data from an international collaboration to determine robust parameters that could inform clinical decision‐making in Pelvic exenteration for locally recurrent rectal cancer.
Hyperspectral imaging for tissue classification, a way toward smart laparoscopic colorectal surgery
The potential of using HSI in colorectal cancer surgery for fast tissue classification, which could improve clinical outcome is shown.
Neoadjuvant ipilimumab plus nivolumab in early stage colon cancer.
- M. Chalabi, L. Fanchi, J. Haanen
- Medicine, BiologyAnnals of oncology : official journal of the…
- 1 October 2018
G.M. Van den Berg, G.L. Lopez-Yurda, A.G. Snaebjornsson, M.E. Van Leerdam, T.N. Voest, J.B. Aalbers, C. Grootscholten, P. Mertz, E. Schumacher, and E.E., Haanen Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands.
Diagnostic performance of imaging for the detection of peritoneal metastases: a meta-analysis
(DW)MRI provided the highest sensitivity for the detection of peritoneal metastases in ovarian and gastrointestinal cancer patients and appears to be the imaging method of choice since it is more available in daily practice than PET(CT).