Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain
- F. Doetsch, I. Caillé, D. Lim, J. García-Verdugo, A. Álvarez-Buylla
- BiologyCell
- 11 June 1999
Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain
- F. Doetsch, J. García-Verdugo, A. Álvarez-Buylla
- BiologyJournal of Neuroscience
- 1 July 1997
The results suggest that chains of migrating neuroblasts in the SVZ may be derived from Type C cells, which had immature ultrastructural characteristics and were nestin-positive but negative to the other markers.
The glial nature of embryonic and adult neural stem cells.
- A. Kriegstein, A. Álvarez-Buylla
- BiologyAnnual Review of Neuroscience
- 25 June 2009
The timing in development and location of NSCs, a property tightly linked to their neuroepithelial origin, appear to be the key determinants of the types of neurons generated.
Long-distance neuronal migration in the adult mammalian brain.
- C. Lois, A. Álvarez-Buylla
- BiologyScience
- 20 May 1994
Grafted and endogenous SVZ cells in the lateral ventricle of adult mice migrate long distances and differentiate into neurons in the olfactory bulb.
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain.
- Z. Mirzadeh, F. Merkle, M. Soriano-Navarro, J. García-Verdugo, A. Álvarez-Buylla
- BiologyCell Stem Cell
- 11 September 2008
EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells
- F. Doetsch, L. Petreanu, I. Caillé, J. García-Verdugo, A. Álvarez-Buylla
- BiologyNeuron
- 19 December 2002
Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain
- B. Menn, J. García-Verdugo, Cynthia Yaschine, Ó. González-Pérez, D. Rowitch, A. Álvarez-Buylla
- BiologyJournal of Neuroscience
- 26 July 2006
The number of oligodendrocytes derived from type B cells in vivo increased fourfold after a demyelinating lesion in corpus callosum, indicating that SVZ astrocyes participate in myelin repair in the adult brain.
Astrocytes Give Rise to New Neurons in the Adult Mammalian Hippocampus
- B. Seri, J. García-Verdugo, B. McEwen, A. Álvarez-Buylla
- BiologyJournal of Neuroscience
- 15 September 2001
It is shown that SGL cells, which express glial fibrillary acidic protein and have the characteristics of astrocytes, divide and generate new neurons under normal conditions or after the chemical removal of actively dividing cells.
Mosaic Organization of Neural Stem Cells in the Adult Brain
- F. Merkle, Z. Mirzadeh, A. Álvarez-Buylla
- BiologyScience
- 20 July 2007
It is shown that postnatal stem cells in different regions produce different types of neurons, even when heterotopically grafted or grown in culture, which suggests that rather than being plastic and homogeneous, neural stem cells are a restricted and diverse population of progenitors.
In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain.
- H. Wichterle, D. Turnbull, S. Nery, G. Fishell, A. Álvarez-Buylla
- BiologyDevelopment
- 1 October 2001
It is demonstrated that LGE and MGE cells migrate along different routes to populate distinct regions in the developing brain, and it is shown that the MGE is a major source of neurons migrating dorsally and invading the developing neocortex.
...
...