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We present a methodology for the active control of time-harmonic wave fields, e.g., acoustic disturbances, in composite regions. This methodology extends our previous approach developed for the case of arcwise connected regions. The overall objective is to eliminate the effect of all outside field sources on a given domain of interest, i.e., to shield this(More)
BACKGROUND A critical challenge in cell biology is quantifying the interactions of cells with their extracellular matrix (ECM) environment and the active remodeling by cells of their ECM. Fluorescence microscopy is a commonly employed technique for examining cell-matrix interactions. A label-free imaging method would provide an alternative that would(More)
Surface plasmon resonance imaging (SPRI) is a label-free technique that can image refractive index changes at an interface. We have previously used SPRI to study the dynamics of cell-substratum interactions. However, characterization of spatial resolution in 3 dimensions is necessary to quantitatively interpret SPR images. Spatial resolution is complicated(More)
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