A. V. Stolin

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A SPECT / X-ray CT system configured at Johns Hopkins University to image the biodistribution of radiopharmaceuticals in unrestrained, un-anesthetized mice has been constructed and tested on awake mice. The system was built by Thomas Jefferson National Accelerator Facility and Oak Ridge National Laboratory. SPECT imaging is accomplished using two gamma(More)
We are developing the HelmetPET, a wearable human PET brain imager which has the potential application of evaluating brain function utilizing PET based radiopharmaceuticals in standing, balancing or moving patients. The HelmetPET is composed of two rings of radiation detectors together providing a cylindrical reconstructed volume with an axial length of 5(More)
Our group is developing a scanner that combines x-ray, single gamma, and optical imaging on the same rotating gantry. Two functional modalities (SPECT and optical) are included because they have different strengths and weaknesses in terms of spatial and temporal decay lengths in the context of in vivo imaging, and because of the recent advent of multiple(More)
In this paper, the capabilities of a wide-area gamma ray photosensor based on a SiPM array are investigated. For this purpose, we have mounted an array of 144 (12&#x00D7;12) SiPMs with individual active area of 3 &#x00D7;3 mm<sup>2</sup> and a pitch of 4.2 mm, thus covering an active area of 50.2 &#x00D7;50.2 mm<sup>2</sup>. The measurements were performed(More)
We describe the design and performance of a dual-modality system for small animal imaging combining a high resolution SPECT component with an X-ray CT component. All components are mounted on a barrel type gantry which is able to rotate in 0.001 degrees increments about the animal. The SPECT subsystem consists of a four custom-built gamma cameras. The(More)
There are opportunities for the development of new tools to advance plant biology research through the use of radionuclides. Thomas Jefferson National Accelerator Facility, Duke University, West Virginia University and the University of Maryland are collaborating on the development of radionuclide imaging technologies to facilitate plant biology research.(More)
In this paper we describe the results of our characterization of four X-ray detectors in order to determine their relative strengths and weaknesses for use in the CT component of a dedicated CT-SPECT scanner that we are developing for small animal imaging. Two of the four detectors are custom-built charge coupled device (CCD)-based detectors and the other(More)
The goal of this study was to evaluate the efficacy of operating a two-head gamma camera system in a configuration in which the two cameras are positioned on opposite sides of the compressed breast, aligned precisely with each other and with precisely anti-parallel viewing directions. The main objective of the present study was to determine if the(More)
While the performance of most current commercially available PET scanners is sufficient for many standard clinical applications, some specific tasks likely require specialized imaging systems. The goal of this project is to explore the capabilities and limitations of a small, high-resolution prototype system for obtaining PET images. The scanner consists of(More)
We are developing a dedicated high resolution (sub-mm), high efficiency, and very fast (with live reconstruction) prostate PET imager composed of an endorectal PET probe and two PET panel modules placed close to the patient on the opposite side of the prostate, and operating in coincidence with the probe. The immediate live image feedback will be primarily(More)