A. V. Dolzhikov

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Associations between 5-HTR2A -1438A/G and 5-HTR2C Cys23Ser polymorphisms and depression and its severity were studied in CHD patients with consideration for the trigger factors, pathogenetic characteristics of CHD, and personal anxiety. The study was carried out in 169 men aged 31-84 (59.0±8.8) years with verifi ed CHD. Depression was more severe (Hamilton(More)
In a framework of search for early predictors of depression in patients with ischemic heart disease (IHD) we studied effect of molecular-genetic factors (polymorphism of brain-derived neirotrophic factor--BDNF), personality traits (anxiety, neuroticism), IHD severity, and psychosocial stressors on manifestations of depression in men with verified diagnosis(More)
OBJECTIVE To compare psychometric and molecular-genetic characteristics of depression caused by ischemic heart disease (IHD) and depression in patients with IHD caused by other psychogenic factors. MATERIAL AND METHODS One hundred and thirty-five patients with depression comorbid to ischemic heart disease (IHD) were examined. Depression was associated(More)
Depression is commonly present in patients with coronary heart disease (CHD). Identification of early predictors of depression in CHD patients is an important direction of current research in the field of psychosomatic medicine. Serotonin transporter gene polymorphism (5-HTTLPR) was earlier reported to contribute to the development of depression comorbid to(More)
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