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Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS), a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-type transcriptional regulator (LTTR) protein PqsR (MvfR) is a key component of alkyl-quinolone (AQ)-dependent QS in Pseudomonas aeruginosa. PqsR is activated by(More)
A series of 3-oxo-C12-HSL, tetramic acid, and tetronic acid analogues were synthesized to gain insights into the structural requirements for quorum sensing inhibition in Staphylococcus aureus. Compounds active against agr were noncompetitive inhibitors of the autoinducing peptide (AIP) activated AgrC receptor, by altering the activation efficacy of the(More)
A bstract . We study in one dimension the semi-classical limit of the exact eigenfunction Ψh E(N,h) of the Hamiltonian H = − 1 2 h2∆ + V (x), for a potential V being analytic, bounded below and lim|x|→∞ V (x) = +∞. The main result of this paper is that for any given E > minx∈R1 V (x) with two turning points, the exact L2 normalized eigenfunction |Ψh E(N,h)(More)
and Rotation-Modulation Collimators [5, 61 have been extensively employed in 7-ray astronomy due to their high transparency, which is important for obtaining maximum detection efficiency. Their performance is superior to conventional collimators for point sources, but deteriorates severely for extended sources. Compton-scatter y-ray imagers have also been(More)
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