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The effect of renal function on enalapril kinetics
- D. Lowenthal, J. D. Irvin, +7 authors K. Harris
- Clinical pharmacology and therapeutics
- 1 December 1985
Enalapril maleate (MK‐421), a nonmercapto‐containing angiotensin converting enzyme (ACE) inhibitor, is converted in vivo to enalaprilat (MK‐422), the active diacid. We evaluated serum profiles and… Expand
[Experiences with isolated organ studies on pathological human arteries].
Pathological, muscular arteries (common and superficial femoral [FC, FS], anterior and posterior tibial [TA, TP] arteries) of patients suffering from arteriosclerosis obliterans (ASO),… Expand
Comparative in vitro study of RGH-2981, a new peripheral blood flow enhancer on animal and pathological human arteries.
The aim of the present investigation was to compare the activity of RGH-2981 and two reference compounds, verapamil and LY 53857 on isolated, normal animal and pathological human arteries. The… Expand