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The present study was undertaken to investigate the effects of extracellular pH (pHe) and intracellular pH (pHi) on 5-hydroxytryptamine (5-HT)-induced contraction and Ca2+ mobilization in vascular smooth muscles. Strip preparations of the rabbit basilar artery without endothelium were loaded with 40 microM fura-2-AM and 2 microM BCECF-AM and mounted in an(More)
This study investigates changes in intraocular pressure (IOP) in rabbits during head-down tilt (HDT), which is commonly used as an experimental model to simulate microgravity. IOP was measured by the needle insertion technique (IOPNEEDLE) and Tono-pen tonometry (IOPTONO-PEN). Although the absolute value of the IOPTONO-PEN was significantly smaller than that(More)
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