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The various parameters of the auditory brainstem response (ABR) undergo distinct maturational transformations in early life. The multiplicity of observed changes suggests unique timetables for development of the contributing neural elements. Although the precise physioanatomic substrate of the ABR remains speculative, experimental manipulations and(More)
Average brainstem potentials evoked by auditory stimuli were recorded from the scalp's surface of human newborns and infants, 6 weeks, 3 months, 6 months and 1 year of age as well as from normal adults. The auditory processes related to peripheral transmission (PT) and central transmission (CT) were shown to mature at differential rates during the first(More)
Since maturation of ABR amplitude and latency in principle are dependent on innate as well as environmental factors and the health of the infant, it is conceivable that prematurely born infants show a maturation profile that is different from that of full term infants. In order to unequivocally address this we analyzed ABRs recorded in 465 full term infants(More)
Middle component AERs to brief click stimuli were recorded from 60 subjects in four age groups to assess age effects on waveform, latency, and amplitude. Replicable responses similar in waveform to those recorded in adults were observed in 3 - 4-year-old children, full-term newborns, and premature infants tested as early as the 31st postconceptional week.(More)
Low-frequency tone bursts (250, 500 and 1 000 Hz) were used to elicit frequency-following responses (FFRs) from full-term, healthy neonates. Easily identifiable FFRs were recorded from all well babies with stimulation at low-to-moderate levels (30-45 dB HLn). The amplitude and threshold values of neonatal FFRs were not significantly different from those of(More)
The purpose of this research was to examine changes in the ratio and amplitude of the N40 component of the auditory event-related potential (ERP) in the paired conditioning (C) test (T) stimulation paradigm following subchronic cocaine/vehicle administration. Free moving rats received cocaine (47.5 mg/kg) or saline for 7 consecutive days in a longitudinal(More)
OBJECTIVE To assess the feasibility of obtaining transient-evoked otoacoustic emissions (TEOAEs) directly in the nursery, to examine the nature of failures in this population, and to determine the time requirements for this test relative to the auditory brain stem response (ABR). DESIGN TEOAEs and ABRs were recorded from 149 ears, at bedside, in the(More)
Brainstem auditory evoked potentials (BAEP's) were recorded from 641 subjects in eleven age groups ranging from birth through adulthood, including three levels of prematurity, in order to establish an age-specific normative data base. The amplitude and latency values for waves 1-6, interwave differences for 3-1, 5-3, 5-1 and the amplitude ratios for 5/3 and(More)