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Plasma imipramine and desmethylimipramine concentrations and depression ratings were measured over a 3 week period in 3 groups of hospitalised depressed patients given standard doses of imipramine. The first group received imipramine alone, the others either amylobarbitone or nitrazepam in addition as a night sedative. The plasma antidepressant levels were(More)
Fifty-one long-stay psychiatric patients admitted to a new rehabilitation unit were followed up for 3-4 years. Two groups were identified, one (n = 29) where significant progress had been made, and a second (n = 22) where no significant progress had been made. The groups were compared on a number of demographic measures and on measures of mental state,(More)
Six elderly psychiatric and 17 mentally handicapped individuals suffering from severe constipation received 3 week periods of treatment with 10 g unrefined bran, three bran biscuits, and Senokot syrup daily or three times weekly. There was no significant difference in the number of bowel movements or enemas or in the consistency of the motions. The results(More)
Two hundred years ago Joseph Cox published his book on the treatment of insanity. His novel technique was rotating the body in a specially designed chair. Initially modest and later extravagant claims were made for the therapeutic benefit of 'Cox's chair'. It was widely adopted in Europe in the first decades of the nineteenth century, but lost favour(More)
The Delusions-Symptoms-States Inventory (DSSI) was administered to 33 chronic non-paranoid schizophrenic patients resident on long-stay wards. It was found that the vast majority of cases (81 per cent) produced symptom patterns conforming to the hierarchy of classes of personal illness model, but with a radically different distribution among the classes(More)
The effects after 1 year of the introduction of a token economy system into a long-term male psychiatric ward of 45 mainly schizophrenic patients are described. The main objectives were (1) to define the limits of such programmes in "average" National Health Service conditions, where additional resources in staff, finance, and facilities are very limited(More)