A. S. Loginov

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Cycloheximide in sublethal doses caused apoptosis in liver cells in vivo, inducing c-myc, c-fos, c-jun and p53 genes and accumulation of sphingosine, a toxic product of the sphingomyelin cycle. These data support the hypothesis that continuous synthesis of labile protective proteins is required to restrain apoptosis in liver; sphingosine might be important(More)
The acid-induced cloud-point extraction (CPE) technique based on sodium dodecylsulfate (SDS) micelles has been used for preconcentration of ten representatives of polycyclic aromatic hydrocarbons (PAHs) for the following fluorescence determination. The effect of the acidity of solution, SDS and electrolyte concentrations, centrifugation time and rate on the(More)
Characteristics of optical recognition programs are described from the standpoint of typical recognition program modules. Not only quality criteria for the separate character recognition but also parameters of other important stages of document input, such as character boundary segmentation, binarization, page segmentation, and storing results, are(More)
Seven patients with primary biliary cirrhosis were treated with rifampicin administered for 2 weeks in a daily dose 450-600 mg. Due to the treatment the itch disappeared completely in 4 and decreased significantly in 3 patients. As shown by the antipyrine test, half-life and clearance of antipyrine returned to normal suggesting cytochrome P-450 induction as(More)
AIM Investigation of activity of copper-containing enzymes in plasma superoxide dismutase (SOD) and ceruloplasmin (CP) in comparison with concentrations of lipoproteins (LP) of the main classes in patients with chronic hepatic diseases (CHD). MATERIALS AND METHODS SOD activity, CP and LP in plasma were measured in 90 patients with CHD. RESULTS An(More)
AIM To examine clinical, immunological and morphological features of HGV- and TTV-infections in patients with chronic hepatic diseases (CHD) and assess efficiency of treatment of HGV-seropositive patients. MATERIAL AND METHODS 202 patients with CHD were examined for markers of HBV-, HCV-, HGV- and TTV-infections. Some patients were subjected to puncture(More)