A. S. Korotina

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A sensitive nonradioactive method for detection of substances interacting with the neuronal α7-type nicotinic acetylcholine receptor (AChR) was proposed. The method uses biotinylated α-cobratoxin (Bt-CTX) and is based on the ability of the N-terminal ligand-binding extracellular domain (LBED) of AChR to interact with α-cobratoxin (CTX) as does the whole(More)
A sensitive nonradioactive method for detection of substances interacting with the neuronal nicotinic acetylcholine alpha 7-type receptor (AChR) was proposed. The method uses biotinylated alpha-cobratoxin (Bt-CTX) and is based on the ability of the N-terminal ligand-binding extracellular domain (LBED) of AChR to interact with alpha-cobratoxin (CTX) as does(More)
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