A S Kirsanov

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Diagnosis of amino acid metabolism disorders according to the clinics without laboratory diagnosis is almost impossible in infants with a history of neonatal and/or premorbid background and multi-organ failure. Mortality due to hereditary tyrosinemia type I is greater than 90%.
Technique of quantitative Gas--chromatographic determination of acrylic acid nitrile and acetonitrile in the blood was developed. Range of detectable concentrations was 1-600 mg/l. Postmortal blood samples obtained from 48 victims of fire were analysed. Toxic nitriles were detected in 85.4% of cases and the relation between nitrile contents and(More)
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