A. S. Arkhipova

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The synthesis of pharmacologically active 2′-deoxynucleoside analogs, namely 2′,3′-dideoxythymidine (I) and 2′,3′-dideoxy-3′-fluorothymidine (II), is described. The proposed approach consists in condensation of the corresponding thioglycosides with silylated thymine using N-bromosuccinimide as a promoter. In the case of compound II, it is shown that the(More)
The investigation quantitatively determined the content of low-molecular-weight aromatic compounds of microbial origin in the sera of 34 individuals by chromatographic mass spectrometry. An "Agilent Technogies 6890N" gas chromatograph with a 5973 mass selective detector was applied; chromatographic separation of components was effected on an Hp-5MS quartz(More)
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