A. Rey

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The purpose of this study was to analyze differences in reality judgements made by subjects and their sense of presence when using the virtual reality (VR) settings of different VR workstations. The two workstations were (1) a high impact computer graphics workstation (Silicon Graphics) with a high quality head mounted display (FS5, Virtual Research) and a(More)
Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair through down regulating Ku70/80 expression. Hypoxia induces drug resistance in clinical tumours, although the mechanism is not clearly elucidated. Vaults(More)
Tirapazamine is a novel bioreductive agent with selective cytotoxicity against hypoxic tumour cells. Synergy with cisplatin and other chemotherapeutic agents has been shown in preclinical trials. Pharmacokinetic studies of tirapazamine have revealed that exposure increases with dose over the range of 18-450 mg m(-2) for a single dose and of 9-390 mg m(-2)(More)
OBJECTIVE To explore the role of Major Vault Protein (MVP) in oral cavity squamous cell carcinoma patients. SUBJECTS AND METHODS 131 consecutive patients suffering from oral cavity squamous cell carcinoma were included in the study. In the whole series, the mean follow-up for survivors was 123.11 ± 40.36 months. Patients in tumour stages I and II were(More)
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