A. R. Kotovskaya

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The objectives of this investigation were to study the effects of thigh cuffs (bracelets) on cardiovascular adaptation and deconditioning in 0 g. The cardiovascular parameters of six cosmonauts were measured by echocardiography, Doppler, and plethysmography, during three 6-month MIR spaceflights. Measurements were made at rest during preflight (−30 days),(More)
Objectives & method: (1) assess the main cardiac and vascular hemodynamic changes induced by the 0.g. (2) evaluate, the astronaut orthostatic tolerance, inflight, using LBNP. The ultrasound device "As.de.Coeur" with Echo, Doppler, TM, & plethysmograph modes was used.
UNLABELLED Cardiovascular adaptation was evaluated on 2 astronauts: one wearing thigh cuffs from flight day 1 to 8 (14d flight), the second without cuffs (21d flight). Ultrasound investigations were performed at rest and during LBNP. RESULTS Without thigh cuffs the cardiovascular adaptation consists in (1) the development of a hypovolemia with an increase(More)
The problem of artificial gravity (AG) in long-term missions is one of the hottest, as the existing countermeasures do not fully cope with the negative consequences of weightlessness. From two variants of AG creation--rotation of space systems around of their mass center or short radius centrifuge (SAC)--the preference is given to SAC, as technically easier(More)
In the 18.5-day flight of the Soviet biosatellite Cosmos-936 (3-22, August 1977) com-parative investigations of the physiological effects of prolonged weightlessness (20 rats) and artificial gravity of 1 g (10 rats) were carried out. Throughout the flight artificial gravity was generated by means of animal rotation in two centrifuges with a radius of 320mm.(More)
The goal of this study was to analyze and generalize hemodynamic data collected over 20 years from 26 cosmonauts, who had flown from 8 to 438 days aboard orbital stations Salut-7 and Mir. This paper describes the results of ultrasonographic studies of the heart and arterial and venous peripheral vessels in different parts of human body as well as the study(More)
Ultrasound Doppler imaging and electrocardiography were used to study hemodynamic responses to spaceflight onboard the Mir space station. Cardiovascular adaptation was studied at rest and during the use of thigh cuffs or "Bracelets" for weightlessness countermeasures. Specific changes in hemodynamic parameters are presented and discussed, along with an(More)
Assess the 0.g induced cardiac and vascular changes at rest on two cosmonauts: one using thigh cuffs from flight day 1 to 8 (Mir 14d flight) the second one not using thigh cuffs (Mir 21d flight). Both were not using intensively any other countermeasure. The ultrasound device onboard Mir with Echo, Doppler, and TM, modes was used.
Lower body negative pressure (LBNP) was used during the Mir spaceflight in a study of orthostatic tolerance. Hemodynamic responses were measured including heart rate, blood pressure, cerebral artery blood flow, and lower limb vascular resistance. Results showed that femoral flow volume decreased, which may be due to hypovolemia and reduced cardiac output.(More)