A. R. Hartman

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Bcl-2 has been associated with both oxidative and antioxidative effects in vivo. Moreover, despite evidence that Bcl-2 is antiapoptotic by virtue of its effect on reactive oxygen species and their scavengers, Bcl-2 exerts its antiapoptotic effects even under anaerobic conditions. The reasons for the variable relationship between Bcl-2 and reactive oxygen(More)
A 33-year-old woman with a strong family history of breast cancer who was referred for mammography 5 weeks after completing lactation was found to have new diffuse bilateral microcalcifications in the breast ducts. Contrast material-enhanced magnetic resonance imaging of the breast showed bilateral patchy areas of abnormal enhancement. Large-core needle(More)
The cellular proto-oncogene c-myc can acquire transforming potential by a number of different means, including retroviral transduction. The transduced allele generally contains point mutations relative to c-myc and is overexpressed in infected cells, usually as a v-Gag-Myc fusion protein. Upon synthesis, v-Gag-Myc enters the nucleus, forms complexes with(More)
9535 Background: Atypical breast duct cells in patients at increased risk of breast cancer have been predictive of subsequent breast cancer. It has been reported that women whose breasts yield no fluid on nipple suction aspiration have lower risk for breast cancer than women whose breasts yield fluid; publications on ductal lavage (DL) have reported attempt(More)
1035 Background: Atypical breast duct cells in patients at increased risk of breast cancer have been predictive of a 5-fold increased breast cancer incidence. While ductal lavage is an FDA approved procedure, very little is known about the anatomy of the ductal system and when atypia is identified, how to localize the lesion when imaging tests are normal.(More)
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