A. Pay

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Series of estrone based analogs were synthetically investigated at positions C-9, C-11, C-16, and C-17 positions, to be biologically evaluated via assessment of cell proliferation, cytotoxicity, and estrogenic/anti-estrogenic activity. LA-7 and LA-10 revealed their potential to exhibit inhibitory estrogenic profile. This was further validated by Estrogen(More)
An architecture is presented which provides clinical information systems with access to vital sign information from medical devices. Middleware components encapsulate details of communicating with devices, whilst adoption of de facto and international standards maximizes interoperability with client software. An application in routine clinical use is(More)
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