A. P. Stankyavichyus

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
A number of a -d ica rbony l compounds possess antihypoxic proper t ies , usually attributed to the par t ic i pation of these agents in e lectron t r ans fe r at cer tain points in the chain of r e sp i r a to ry enzymes [1]. One of these compounds with favorable evaluation is isatin [2]. Its der ivat ives a re also of interest , par t icular ly those that(More)
3 6 , 6 5 3 6 5 7 ( 1 9 8 3 ) . 5. M. L. Belen'kli, Elements of Quantitative Evaluation of Pharmacological Effect [in Russian], Riga (1959). 6. L. J. Ballamy, Infrared Spectra of Complex Molecules, Wiley (1958). 7. E. S. Markaryan and R. S. Balayan, Arm. Khim. Zh., 29, 704-707 (1976). 8. E. A. Markaryan andR. S. Balayan, Inventor's Certificate No. 572045(More)
In [6] we presented data on the antihypoxic activity of isatin (I) and its derivatives that have various substituents on the pyrrole nitrogen and in the benzene ring. That study indicated the interconnection between the degree of the compounds' antihypoxic effect and li~ophiiic index (R~ as well as the first half-wave potential of electrochemical reduction(More)
i. V. M. Votyakov and E. I. Boreko, Metho&~cal Problems of the Scientific Development of Antiviral Agents [in Russian], Minsk (1977), pp. 10-14. 2. I. Ya. Grava, Ya. Yu. Polls, M. Yu. Lidak, et al., Khim.-farm. Zh., No. I0, 42-45 (1980). 3. L. V. Denisova, L. I. Nikonovich, V. A. Saikovskaya, et al., Molecular Biology of Viruses: Chemotherapy and(More)
1 A.L. Mndzhoyan and O. L. Mndzhoyan, Dokl. Akad. Nauk Arm. SSR, 21, No. 3, 27-32 (1955). 2 A.L. Mndzhoyan and O. L. Mndzhoyan, Dokl. Akad. Nauk Arm. SSR, No. i, 17-25 (1955). 3 O.L. Mndzhoyan and E. R. Bagdasaryan, Arm. Khim. Zh., 19, No. 9, 716-721 (1966). 4 J.F. Carmichael and W. S. Port, J. Org. Chem., 26, 2681-2688 (1961). 5 H. Cilman and C. S.(More)
pending on the substituent in the 4-position of the quinoline ring. For example, the carboxy group in (IV) led to the appearance of moderate antifungal and weak antistaphylcoccal activity. Replacement by the ethoxycarbonyl group (VI) resulted in the loss of antimicrobial activity, while the ethoxycarbonylamino residue conferred antimicrobial activity(More)
i. M. L. Belen'kii, Elements of the Quantitative Evaluation of Pharmacological Effects [in Russian], Riga (1959), pp. 71-92. 2. Zh. A. Goloshchapova, T. N. Tuzhilkova, and L. I. Mizrakh, Radiobiologiya, No. 4, 521-525 (1981). 3. S. S. Kuznetsova, Problems of General Radiobiology [in Russian], Moscow (1971), pp. 180-190. 4. Methodical Directions for the(More)
Acute toxicities were determined by a standard method [2], terminal anesthesia was determined in the rabbit eye by the Regnier--Valeeta method [3], analgesic activity by the hot plate method (t = +55~ [7], and anticonvulsant activity by means of the effects of the compounds on convulsions modeled in mice by the administration of arecoline, corazole, and(More)
We [8] and other authors [12] have already shown that the quaternization of the amino group of Inderal [propranolol hydrochloride] intensifies the antiarrhythmic effect, while side effects, characteristic of 8-adrenoblocklng agents become weakened. Later we found [9] that the character of the substituent at the quaternary nitrogen atom sharply changes the(More)
In extensive research carried out on the antiviral activity of compounds structurally similar to methisazone (l-methylisatin-3-thiosemicarbazone, see review [2]), the corresponding benzo derivatives have been insufficiently investigated [5]. It was our aim to synthesize and study the properties of B-hydrazones of angular benzisatins (I-XVI), while taking(More)
  • 1