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  • A Nusrat, Murielle Giry, +6 authors James L. Madara
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1995 (First Publication: 7 November 1995)
  • The rho family of GTP-binding proteins regulates actin filament organization. In unpolarized mammalian cells, rho proteins regulate the assembly of actin-containing stress fibers at the cell-matrixContinue Reading
  • A Nusrat, Charles A Parkos, +4 authors James L. Madara
  • Biology, Medicine
  • The Journal of clinical investigation
  • 1994 (First Publication: 1 May 1994)
  • Intestinal epithelial cells rest on a fibroblast sheath. Thus, factors produced by these fibroblasts may influence epithelial function in a paracrine fashion. We examined modulation of intestinalContinue Reading
  • A Nusrat, Charlene Delp, James L. Madara
  • Biology, Medicine
  • The Journal of clinical investigation
  • 1992 (First Publication: 1 May 1992)
  • Closure of superficial wounds in epithelia occurs by migration of cells shouldering the wound. We describe an in vitro model of such restitution using a human intestinal epithelial cell line, T84.Continue Reading
  • Didier Merlin, Lianwei Jiang, +4 authors James L. Madara
  • Medicine, Chemistry
  • American journal of physiology. Cell physiology
  • 1998 (First Publication: 1 August 1998)
  • Monolayers of the human colonic epithelial cell line T84 exhibit electrogenic Cl- secretion in response to the Ca2+ agonist thapsigargin and to the cAMP agonist forskolin. To evaluate directly theContinue Reading