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OBJECTIVES To evaluate the performance of a single-nucleotide polymorphism (SNP)-based non-invasive prenatal test (NIPT) for the detection of fetal 22q11.2 deletion syndrome in clinical practice, assess clinical follow-up and review patient choices for women with high-risk results. METHODS In this study, 21 948 samples were submitted for screening for(More)
  • A Norvez
  • 1997
In 1992, in the public sector, 18% of child deliveries took place in small maternity centres having less than 15 beds. In 1981, the percentage has fallen to 11%. In the private sector, the two proportions were respectively 30% and 11%. From the demographic point of view, the process of urbanization and the sharp decrease in the overall birth rate explain(More)
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