A. N. Healey

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The authors assessed rats' encoding of the appearance or egocentric position of objects within visual scenes containing 3 objects (Experiment 1) or 1 object (Experiment 2A). Experiment 2B assessed encoding of the shape and fill pattern of single objects, and encoding of configurations (object + position, shape + fill). All were assessed by testing rats'(More)
The aims of this study were to evaluate several clinical and instrumental parameters in a large number of patients with constipation and incontinence as well as in healthy controls and discuss their potential implications in the functional aspects of these disorders. Eighty-four constipated and 38 incontinent patients and 45 healthy controls were submitted(More)
Hippocampal-lesioned rats (HPC) and sham controls (SH) learned constant-negative visual discriminations among scenes in a Y-maze. Any arm could be start arm for a trial. Two choice scenes ("constant" and "variable") were shown in the other arms. In Experiment 1, each problem had 2 constants. One or the other constant appeared on every trial, and the(More)
Rats with fornix transection, or with cytotoxic retrohippocampal lesions that removed entorhinal cortex plus ventral subiculum, performed a task that permits incidental learning about either allocentric (Allo) or egocentric (Ego) spatial cues without the need to navigate by them. Rats learned eight visual discriminations among computer-displayed scenes in a(More)
Rats learned discriminations in which 2 familiar compound visual stimuli AB and CD were nonreinforced, whereas less-familiar compounds (EF, GH, IJ...) were reinforced (constant-negative paradigm). Such discriminations can in principle be acquired through elemental (nonconfigural) learning. Three different types of compound--object/object, object/position,(More)
BACKGROUND/AIMS Primary adrenal insufficiency (AI) is an important cause of morbidity in children. Our objectives were: (1) to describe the clinical presentation of children with new-onset primary AI, and (2) to identify monogenic causes of primary AI in children. METHODS Chart review and mutation detection in candidate genes were conducted for 11(More)
The new millennium was a turning point for the scrutiny of quality and safety in healthcare. An increasing number of studies, investigations, reports and audits worldwide acknowledge that there is a significant risk of unintentional harm to surgical patients. The reasons for this are complex, but, in broad terms, surgical systems are to some degree failing(More)
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