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BACKGROUND The recent discovery of a new myokine (irisin) potentially involved in health-related training effects has gained great attention, but evidence for a training-induced increase in irisin remains preliminary. Therefore, the present study aimed to determine whether irisin concentration is increased after regular exercise training in humans. (More)
PURPOSE This study aimed to investigate the effects of a 6-month preventive resistance training program on resting metabolic rate (RMR) and its associations with fat-free mass (FFM) and the newly described myokine irisin as two potential mechanistic links between exercise training and RMR. METHODS In a randomized controlled trial, 74 sedentary healthy(More)
The concept of Virtual Monte Carlo (VMC) has been developed by the ALICE Software Project to allow different Monte Carlo simulation programs to run without changing the user code, such as the geometry definition, the detector response simulation or input and output formats. Recently, the VMC classes have been integrated into the ROOT framework, and the(More)
ALICE, the experiment dedicated to the study of heavy ion collisions at the LHC, uses an object-oriented framework for simulation, reconstruction and analysis (AliRoot) based on ROOT. Here, we describe the general ALICE simulation strategy and those components of the framework related to simulation. Two main requirements have driven the development of the(More)
The concept of Virtual Monte Carlo (VMC) has been developed by the ALICE Software Project to allow diierent Monte Carlo simulation programs to run without changing the user code, such as the geometry deenition, the detector response simulation or input and output formats. Recently, the VMC classes have been integrated into the ROOT framework, and the other(More)
Since its release in 1999, the LHC experiments have been evaluating Geant4 in view of adopting it as a replacement for the obsolescent Geant3 transport MonteCarlo. The ALICE collaboration has decided to perform a detailed physics validation of elementary hadronic processes against experimental data already used in international benchmarks. In one test,(More)
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