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BACKGROUND Catechol-O-methyltransferase (COMT) has been investigated as a candidate gene in many neurologic disorders involving catecholaminergic systems. The NlaIII restriction site polymorphism (RSP) at COMT is a G<-->A (site absent<-->site present) single nucleotide polymorphism (SNP) at nucleotide 322/472 (in the short or long mRNA) that results in a(More)
Most neuroimaging studies of language function to date use a block-subtraction paradigm in which images acquired during relatively long periods of target stimuli are compared to those acquired during a control period. These studies typically require an overt response on the part of the subject, usually some type of discrimination or grammatical judgment by(More)
BACKGROUND The dopamine transporter (DAT) is the primary mechanism for dopamine clearance from the synapse in midbrain dopaminergic neurons, and the target of psychostimulant and neurotoxic drugs such as cocaine, amphetamine, and MPTP. Consequently, the gene for DAT (SLC6A3) has been the focus of many population-based case-control association studies using(More)
The shape of the pharynx has a large effect on the acoustics of vowels, but direct measurement of this part of the vocal tract is difficult. The present study examines the efficacy of inferring midsagittal pharynx shape from the position of the tongue, which is much more amenable to measurement. Midsagittal magnetic resonance (MR) images were obtained for(More)
The ability of speakers to exaggerate speech sounds ("hyperarticulation") has led to the theory that the targets themselves must be hyperspace hyperarticulated. Johnson, Flemming, and Wright (1993) found that perceptual "best exemplar" choices for vowels were more speech extreme than listeners' own productions. Our first experiment, using their procedure,(More)
The posterior pharyngeal wall has been assumed to be stationary during speech. The present study examines this assumption in order to assess whether midsagittal widths in the pharyngeal region can be inferred from measurements of the anterior pharyngeal wall. Midsagittal magnetic resonance images and X-ray images were examined to determine whether the(More)
We thank Ben Sigman for outstanding work on site definition and data assembly. We also thank Roger vonHaefen for comments, and Nancy Bockstael and John Duffield for help in the early stages of designing our survey. Abstract In this paper we estimate the economic loss of hypothetical beach closures on the Padre Island National Seashore on the Gulf Coast of(More)
Previous studies of scorpion envenomation in the United States (US) have focused on Arizona and the bark scorpion, Centruroides sculpturatus. Although many other scorpion species live in the US, information about envenomations in other states is lacking. Nationwide scorpion exposures from 2005 to 2015 were analyzed using the National Poison Data System. Of(More)
Coral snake bites and envenomation in children: a case series. Background: Around 2 % of venomous snake bites each year in the USA are from the Elapidae (coral snake) family. In Florida alone, there are ~17 cases per year. There has not been a pediatric case series published in ~40 years. The authors describe four cases of confirmed or suspected Micrurus(More)
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