A. Matthew Prina

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OBJECTIVE There have been dramatic societal changes in East Asia over the last hundred years. Several of the established risk factors could have important period and cohort effects. This study explores temporal variation of dementia prevalence in mainland China, Hong Kong and Taiwan taking study methods into account. METHODS Seventy prevalence studies of(More)
The pathogenesis of frailty and the role of inflammation is poorly understood. We examined the evidence considering the relationship between inflammation and frailty through a systematic review and meta-analysis. A systematic literature search of papers providing data on inflammatory biomarkers and frailty was carried out in major electronic databases from(More)
BACKGROUND There is relative little information about the prevalence and risk factors of co-morbid anxiety and depression in later life. These disorders are often associated with worse response to treatment than either condition alone, and researching their epidemiology in diverse settings is vital to policy makers. We therefore investigated the(More)
BACKGROUND Many of the assessment tools used to study depression among older people are adaptations of instruments developed in other cultural setting. There is a need to validate those instruments in low and middle income countries (LMIC). METHODS A one-phase cross-sectional survey of people aged [greater than or equal to] 65 years from LMIC. EURO-D was(More)
BACKGROUND Half a century after the inception of the term "successful aging (SA)," a consensus definition has not emerged. The current study aims to provide a comprehensive snapshot of operational definitions of SA. METHODS A systematic review across MedLine, PsycInfo, CINAHL, EMBASE, and ISI Web of Knowledge of quantitative operational definitions of SA(More)
BACKGROUND It is known that people who suffer from depression are more likely to have other physical illnesses, but the extent of the association between depression and non-psychiatric hospitalisation episodes has never been researched in great depth. We therefore aimed to investigate whether depressed middle-aged and older people were more likely to be(More)
OBJECTIVES The aim of the current study was to conduct a systematic review of lay perspectives of successful ageing (SA), synthesise these data using a metaethnographic framework and to provide a snapshot of extant lay perspectives of SA. DESIGN A systematic review of layperson perspectives of SA was conducted across MEDLINE, PsycInfo, CINAHL, EMBASE and(More)
BACKGROUND Anxiety is a common mental disorder among older people who live in the Western world, yet little is known about its prevalence in low- and middle-income countries. AIMS We investigated the prevalence of anxiety and its correlates among older adults in low- and middle-income countries with diverse cultures. METHOD Cross-sectional surveys of(More)
INTRODUCTION In 2010, Alzheimer's Disease International presented estimates of the global cost of illness (COI) of dementia. Since then, new studies have been conducted, and the number of people with dementia has increased. Here, we present an update of the global cost estimates. METHODS This is a societal, prevalence-based global COI study. RESULTS The(More)
BACKGROUND There is lack of information of the hospital costs related to depression. Here, we compare the costs associated with general hospital admissions over 2 years between older men with and without a documented past history of depression. METHODS A community-based cohort of older men living in Perth, Western Australia, was assessed at baseline(More)