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MOTIVATION Gaussian graphical models (GGMs) are a popular tool for representing gene association structures. We propose using estimated partial correlations from these models to attach lengths to the edges of the GGM, where the length of an edge is inversely related to the partial correlation between the gene pair. Graphical lasso is used to fit the GGMs(More)
I would like first to thank my direct team, Andy Fitch, Irène Margiolaki and Jon Wright for all the inestimable help, all the advice and ideas during the last three years. I would like to thank the three students from the University of Bath who worked hard with me, Sotonye Dagogo, Ines Collings and Lucy Saunders. The ID31, ID11, ID14 and BM16 teams for(More)
In the title compound [systematic name 5-de-oxy-5-fluoro-N-(pent-yloxycarbon-yl)cytidine], C(15)H(22)FN(3)O(6), the pentyl chain is disordered over two positions with refined occupancies of 0.53 (5) and 0.47 (5). The furan ring assumes an envelope conformation. In the crystal, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into chains propagating(More)
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