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Felix d'Herelle first demonstrated, about 90 years ago, the presence of bacteriophages in human and animal body microbiota. Our comprehension of the impact of naturally occurring bacteriophages on symbiotic bacteria, and of their role in general homeostasis of macro-organism, nevertheless remains quite fragmentary. Analysis of data in various human- and(More)
Soon after the discovery of bacteriophages in 1917, Felix d'Hérelle demonstrated that they are present in humanand animal-associated microbiota, and speculated that these phages may play certain roles in the immunity against bacterial infections (d'Hérelle 1926). That remains an intriguing but not yet proven possibility up to this day (reviewed in Górski(More)
We developed a novel PCR-fingerprinting system for differentiation of enterobacterial strains using a single oligonucleotide primer IS1tr that matches the inverted terminal repeats of the IS1 insertion element. Compared to widely used BOX-PCR and ribotyping methods, our system features higher resolution allowing differentiation of closely related isolates(More)
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