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Progesterone concentrations in cord artery and vein and in retroplacental and maternal blood were measured in 43 women delivered by caesarean section. The cord vein concentration was consistently higher than the cord artery concentration. The two were correlated but neither was related to the concentration in retroplacental blood. It was concluded that… (More)
All young patients in the Grampian area attending the lymphoma review clinic who had received first line treatment for Hodgkin's disease and had attained complete remission without subsequent relapse were studied between 1980 and 1983. Chemotherapy with MVPP (mustine, vinblastine, procarbazine, and prednisolone) had more severe effects on the fertility of… (More)
A new compound in the triphenylethylene series has been tested for its effect in causing ovulation in secondary amenorrhoea. Twenty patients were given a total of 40 courses of treatment and ovulation resulted in 16 instances. Three patients became pregnant. Probably this compound can induce ovulation in suitable subjects.
A family is reported in which isolated hypogonadotrophic hypogonadism is inherited as an autosomal dominant condition with variable expression. In previous familial cases, inheritance was autosomal recessive. Comparison is made with the endocrine and genetic findings in Kallmann's syndrome, which should be considered a separate disorder. There is difficulty… (More)
Blood was collected from 12 women following Caesarean section or normal delivery at term. The decline in plasma concentration of total oestriol, oestriol sulphate, oestriol glucosiduronate, unconjugated oestriol, human placental lactogen and pregnancy specific beta1 glycoprotein following delivery of the placenta was studied for 120 hours. The steroids and… (More)
Five different products secreted by the fetoplacental unit into the maternal circulation were measured in 272 patients when they were 34 weeks pregnant. The most useful indicator of present pathology or future complications of pregnancy was a placental protein, pregnancy associated plasma protein. A which was raised in pre-eclamptic toxaemia, antepartum… (More)